Therapeutic Effects of Ketogenic Diet Components on Parkinson's Disease

Abstract: Parkinson's disease is a neurodegenerative disease and no proper treatment or cure has been developed for it till now. Worldwide the incidence of disease has been increased with age. Latest researches have focused on the dietary aspects of Parkinson's and have revealed that a ketogenic diet may be benecial in prevention and for therapy. The main aim of this review article was to explore the dietary elements present in ketogenic diet and their respective roles in the body with link to Parkinson's disease. Ketogenic diet has been used in many neurological diseases due to its neuroprotective effects. Ketogenic diet is a normal caloric diet that composed of with high fat (mostly composed with polyunsaturated fatty acids), medium protein and low in carbohydrates. The composition of this diet makes body to utilize fat and ketones for energy by altering glucose. The major constituents present in a ketogenic diet which have neuroprotective effects against Parkinson's are; B complex vitamins, Omega-3 Fatty Acids, Omega-6 Fatty acids and Vitamin D. The benecial effects have been evaluated regarding the role of constituents present in a ketogenic diet on Parkinson's disease. The need for further researches, especially clinical trials for the different constituents of ketogenic diet and their neuroprotective properties are still required. Key Words: Parkinson's Disease, Ketogenic Diet, Omega-3 Fatty Acids, B-Complex Vitamins