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Thalidomide induced xerosis: an unwanted reaction

Journal: International Journal of Basic & Clinical Pharmacology (Vol.5, No. 4)

Publication Date:

Authors : ; ; ; ; ;

Page : 732-735

Keywords : Anemia; Gastric antral vascular ectasia; Thalidomide; Xerosis;

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Abstract

A 59-year-old male exhibited anemia for evaluation. Endoscopy was diagnostic of gastric antral vascular ectasia. He was given a trial of thalidomide after informing about the adverse effects. After starting thalidomide at 100 mg/day, his hemoglobin (Hb) improved. Post 1 month of therapy his Hb normalized, but he developed xerosis. He was given symptomatic treatment, but did not improve. Thalidomide was suspected to cause xerosis, it was discontinued for a month and post-discontinuation of drug he is symptom free for past 8 months. This paper reports a rare case of thalidomide induced xerosis with dermatological and neurological involvement.

Last modified: 2014-10-26 15:29:07