Thalidomide induced xerosis: an unwanted reaction
Journal: International Journal of Basic & Clinical Pharmacology (Vol.5, No. 4)Publication Date: 2014-08-01
Authors : Nagesh Kamath; Anurag Shetty; Harneet Singh; Shiran Shetty; Srinivasa Rao Sirasanagandla;
Page : 732-735
Keywords : Anemia; Gastric antral vascular ectasia; Thalidomide; Xerosis;
Abstract
A 59-year-old male exhibited anemia for evaluation. Endoscopy was diagnostic of gastric antral vascular ectasia. He was given a trial of thalidomide after informing about the adverse effects. After starting thalidomide at 100 mg/day, his hemoglobin (Hb) improved. Post 1 month of therapy his Hb normalized, but he developed xerosis. He was given symptomatic treatment, but did not improve. Thalidomide was suspected to cause xerosis, it was discontinued for a month and post-discontinuation of drug he is symptom free for past 8 months. This paper reports a rare case of thalidomide induced xerosis with dermatological and neurological involvement.
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Last modified: 2014-10-26 15:29:07