ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Nano-N,N,N',N'-tetramethyl-N-(silica-n-propyl)-N'-sulfo-ethane-1,2-diaminium chloride as an efficient and recyclable catalyst for the green synthesis of 3,4‐dihydropyrimidin‐2‐(1H)‐ones/thiones

Journal: Asian Journal of Green Chemistry (Vol.5, No. 1)

Publication Date:

Authors : ; ; ;

Page : 1-11

Keywords : Nanocatalyst Nano-N; N; N'; N'-tetramethyl-N-(silica-n-propyl)-N'-sulfo-ethane-1; 2-diaminium chloride (nano-[TSPSED][Cl]2) 3; 4‐Dihydropyrimidin‐2‐(1H)‐one 3; 4‐Dihydropyrimidin‐2‐(1H)‐thione; Solvent-free;

Source : Downloadexternal Find it from : Google Scholarexternal

Abstract

In this work, efficient and high-yielding green synthesis of 3,4‐dihydropyrimidin‐2‐(1H)‐ones and 3,4‐dihydropyrimidin‐2‐(1H)‐thiones was achieved by a one-pot three-component reaction between aldehydes, ethyl acetoacetate, and urea/thiourea, using a recyclable mesoporous nanocatalyst entitled nano-N,N,N',N'-tetramethyl-N-(silica-n-propyl)-N'-sulfo-ethane-1,2-diaminium chloride (nano-[TSPSED][Cl]2). High yields, short reaction times, solvent-free conditions, easy purification of the products, compliance with green chemistry protocols and recyclability of the catalyst are the benefits of this work. The products were obtained in 80-98 % yields and in 10-45 min.

Last modified: 2020-10-08 03:27:59