Photodynamic Therapy Using Endoscopy Capsule Robot
Journal: Academic Journal of Life Sciences (Vol.6, No. 7)Publication Date: 2020-09-10
Authors : Sherif Hamdy ElGohary; Yomna Sabah Mohamed; Mennatallah Hany Elkhodary; Omnya Ahmed; Mennatallah Hesham;
Page : 93-100
Keywords : Photodynamic therapy; Photosensitizers; Wireless capsule; Endoscopy; Colon cancer; Photochemical reaction.;
Abstract
Among the photosensitizers used in Photodynamic therapy (PDT) technique for cancer treatment, it is found out that the Methylene blue and glycoconjugates chlorine are the best ones for this purpose. In this paper, it is suggested to use Active Capsule Wireless Endoscopy Robot instead of the traditional endoscope. The capsule has many valuable features. It uses LEDs as a source of light in the PDT to kill the colon cancer cells. So, the doctor can make use of the advantage of applying the LED light locally at the tumor which was previously injected by the photosensitizers, the light activates these photosensitizers and a photochemical reaction starts that makes the colon cancer cells die. The light with effective wavelength and power density, energy level and controlled LED light intensity will be applied. Active locomotion capsule endoscopy with an electromagnetic actuation system that can achieve a 3-D locomotion and guidance within the digestive system. The paper also discussed how to manage the required power in the capsule for all parts, LEDs, camera, transceiver, and locomotion.
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Last modified: 2020-10-26 20:17:11