EXPERIENCE OF MANUFACTURING AND APPLICATION OF ANTIBACTERIAL CLINOPTILOLITE-CONTAINING POWDER FOR THE TREATMENT OF I - II STAGES BEDSORES (PRESSURE ULCER)

The causes of decubital ulcers (bedsores) are ischemia and neurotrophic tissue changes caused by chronic compression in patients with insufficient or inadequate care. The results of treatment of 60 cases of stage I-II bedsores in the article are analyzed and prospects of application in clinic practice of local therapy with use of powders based on clinoptilolite are grounded. In 13 patients – 8 patients of the main and 5 patients of the control group confirmed the presence of type II diabetes mellitus. Patients with type II diabetes revealed insulin resistance and expressed of laboratory parameters deviations, HOMA index of insulin resistance (8.11±1.1, р<0.01), glycated hemoglobin (11.1% ±1,5%, р<0.05) and low HOMA indices of pancreatic β-cell function (36.4% ±1.5%, p<0.01), also among some other deviations of metabolism. The criterion for the effectiveness of care and treatment was to reduce exudation with marginal epithelialization, and (or) crust formation. In the patients of the main group, the rate of healing and correction of wounds and macerated areas was 4.8±0.21%, in the control group – 4.0±0.25% (χ2=28.62). The zeolite in the powder composition determines the creation of appropriate environment and conditions of macerated surface, optimal for reparative processes and healing environment, which promotes of healing of macerated areas.