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SYNTHESIS, CHARACTERIZATION AND SKELETAL MUSCLE RELAXANT ACTIVITY FOR NOVEL [1,4]DIAZEPINO[2,3-G]QUINOXALINE DERIVATIVES
Journal: Indian Drugs (Vol.57, No. 09)Publication Date: 2020-09-28
Authors : D. Visagaperumal; Pemmadi Raghuveer Varma; R. Jayakumar; Vineeth Chandy;
Page : 38-44
Keywords : * For Correspondence: vishak_dr@yahoo.co.in;
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Abstract
Novel [1,4]diazepino[2,3-g]quinoxaline derivatives 5a-5i were designed, synthesized and characterized by spectroscopic method and elemental analysis. The title compounds were screened for skeletal muscle relaxant. Among the synthesized analogs, compound 5g and compound 5h revealed significant skeletal muscle relaxant activity. The relationship between the functional group variation and the biological activity of the synthesized compounds is discussed.
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Last modified: 2020-11-10 14:27:14