Serum Adenosine Deaminase Values In Healthy People

The purpose of this study is to determine the activity of serum adenosine deaminase (ADA) in healthy people, in connection with significant differences in published reference ranges from different authors. In our study, we examined 160 healthy subjects aged 18 to 84, of whom 64 were men and 96 women. We have determined serum adenosine deaminase levels using a method based on the ability of the enzyme adenosine deaminase to catalyze the deamination of adenosine to inosine and ammonia. The catalytic concentration is determined spectrophotometrically by the rate of reduction of NADH measured at 340 nm.