Pathomorphological Picture of Lungs of White Rats with Preclinical Study of UVMC «Lizunets»
Journal: International Journal of Mechanical and Production Engineering Research and Development (IJMPERD ) (Vol.10, No. 3)Publication Date: 2020-06-30
Authors : Damir D. Hairullin Elena G. Gubeeva Farit F. Zinnatov Aliya R. Kashaeva Alexander P. Ovsyannikov Azamat H. Shantyz Andrey V. Malnev Damir V. Aleev Guzalia R. Yamalova Kadriya F. Khalikova Gulnara G. Galyautdinova;
Page : 8311-8314
Keywords : Pathomorphology; White Rats; Feed Additives;
Abstract
In order to study the Toxicological properties of carbohydrate-vitamin-mineral concentrate «Lizunets», subchronic toxicity experiments were conducted on clinically healthy mongrel white rats. Animals kept in vivarium conditions were given distilled water inside the control group, and animals of the experimental group were given a feed additive in the form of an aqueous suspension of UVMC «Lizunets» in different doses inside with the help of an atraumatic probe. In experimental animals, the physiological state, behavioral responses, and use of feed and water were studied, so that they did not differ from the control groups of white rats. The results of anatomical and topographical and morphological studies of internal organs and lungs of white rats showed that the use of UVMC «Lizunets» during the study was not accompanied by undesirable changes. Histological examination of the lungs of white rats of experimental and control groups allows us to conclude that no undesirable deviations were detected
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