Review on Novel Drug Delivery System of Microsphere Type, Material, Method of Preparation and Evaluation

The Non ideal pharmaceutical, pharmacokinetic, and therapeutic properties often combine to reduce the effectiveness of certain compounds. For the vectoring of such compounds to target areas, liposomes, nanoparticles, and microspheres have been suggested. Microsphere are spherical in shape so, therapeutic efficacy of microspheres containing drug depends upon their characteristics that can be altered in required terms by altering materials, , methods, polymers or techniques of microsphere.Microspheres are characteristically free flowing powders having particle size ranging from 1 1000 µm consisting of natural or synthetic polymers. Microspheres are used in drug delivery systems which are prepared to obtain prolonged or controlled drug delivery to improve bioavailability, stability and action at the specific site to predetermined rate. Microsphere can be manufactured by various type of material natural, and synthetic in microsphere. Microspheres are various types like Bioadhesive microspheres, Magnetic microspheres, Floating microspheres, radioactive microspheres, Polymeric microspheres, Biodegradable polymeric microspheres, Synthetic polymeric microspheres. microspheres and are prepared by methods like Spray Drying, Solvent Evaporation, Single emulsion technique, Double emulsion technique, Phase separation coacervation technique, Spray drying and spray congealing, Solvent extraction, Quassi emulsion solvent diffusion. Microspheres have wide range of applications and their evaluation parameter. Suraj Rangnath Tandale | Mahesh Muralidhar Mole | Vitthal Ramdas Gawade "Review on Novel Drug Delivery System of Microsphere: Type, Material, Method of Preparation and Evaluation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-6 , October 2020, URL: https://www.ijtsrd.com/papers/ijtsrd35725.pdf Paper Url: https://www.ijtsrd.com/pharmacy/other/35725/review-on-novel-drug-delivery-system-of-microsphere-type-material-method-of-preparation-and-evaluation/suraj-rangnath-tandale