Dynamics of Indicators of Energy-Structural Status in Patients with Ischemic Stroke in Conducting Intensive Therapy

According to the Ukrainian Ministry of Health Center of Medical Statistics, there are 100-120 thousand cases of cerebral stroke in Ukraine per year. The average ratio of hemorrhagic and ischemic strokes is 1:4. Only 8-10% of patients who have suffered a brain stroke return to work. Mortality in the acute period of cerebral stroke reaches 35%, decreasing to 15% at the end of the first year and 43% in the next 5 years after the stroke. Material and methods. We conducted a retrospective, nonrandomized study of 35 critical patients with ischemic stroke (average age 71.1±1.5) at the anesthesiology department with intensive care units of the Multiprofile Clinical Hospital № 9 (Zaporizhzhia city, Ukraine). The study involved 13 male patients (37%) of average age 68.2±2.2, and 22 females (63%) with the average age 73.7±1.9. The diagnosis was established in accordance with the existing criteria for clinical-neurological examination and computer tomography. The severity of ischemic stroke was assessed according to the National Institute of Health Stroke Scale. Results and discussion. Intensive therapy was conducted according to the order of the Ministry of Health of Ukraine № 602 “Unified clinical protocol of medical care – Ischemic stroke (emergency, primary, secondary (specialized) medical care, medical rehabilitation)” dated 03.08.2012. In patients with ischemic stroke, during their entire stay in the department of anesthesiology with intensive care units, there was a systolic destabilization, which was compensatory and completely eliminated in the department of neurology. As a result of the progression of cerebral ischemia, from the 2nd day of patient's stay in the department of anesthesiology with intensive care units, there was a worsening of the energy-structural status clinical danger index. Thanks to the intensive care complex, it can be completely eliminated on the last day of patient's stay in the department of anesthesiology with intensive chambers therapy. Conclusions. Dynamics of energy-structural status, of patients with ischemic stroke were characterized by preserved myocardial energy reserve; hypoosmolar destabilization; adaptability and instability at all stages of the study.