ANTIMICROBIAL EFFECT OF GENTAMICIN INCORPORATED IN HYDROXIAPATITE COATING ON 316L STAINLES STEEL

This study aims on morphological, antibacterial and drug release characterization of a coating based on hydroxyapatite (HA)/with or without gentamicin on 316L stainless steel, in physiological environment. Hybrid materials structure was identified by Fourier transformed infrared spectroscopy (FTIR) and their surface analysis by scanning electron microscopy (SEM). Gentamicin release were studied using a UV-Vis method. Antibacterial properties of coatings were determined by contact method using using agar disc diffusion method for two bacterial strains: S. aureus and E. coli. Antibacterial effect of coating seems to be better for and 316L-HA/gentamicin coating compare to 316L-HA coating for both bacterial strains.