CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF MULTIPLE MYELOMA IN THE RYAZAN REGION

Aim. To determine the clinical and epidemiological characteristics of multiple myeloma (MM) in the Ryazan region in 2019. Materials and Methods. A retrospective analysis of medical histories of 107 patients with MM who were under observation at the hematology department of the state budgetary institution of the Ryazan region Regional Clinical Hospital (RCH) in 2019 was carried out. Registered morbidity implies identification of new cases of MM that were not registered before and were first detected in the current calendar year. Statistical analysis of the obtained data was carried out using Microsoft Office application programs and the methods of descriptive and parametric statistics. Results. In 2019, 107 patients of which 43 were men and 64 women aged 34-84 years (mean age 66.2±9.3 years), were under observation at the hematology department of the RCH. The ratio of men to women was 1.0 to 1.49, which reflects the all-Russian tendency. 3.77% Of patients with MM had IIA stage of the disease, 62.26% had IIIA stage, and 33.96% had IIIB stage of myeloma. The morbidity with MM in the Ryazan region in 2019 was 3.23 per 100 000 people. Conclusion. The incidence of the disease in the Ryazan region in 2019 was higher than the average for Russia, which may be due to the diagnostic capabilities of the region with the existence of a specialized hematological department and an outpatient hematology service. In the age group of MM, patients aged 60-74 years predominated, women predominated in the gender structure. Among patients with MM in the Ryazan region, patients with III stage disease (96.22%) predominated.