COMPARISION OF RETINAL NERVE FIBRE LAYER THICKNESS BY CIRRUS HD-OPTICAL COHERENCE TOMOGRAPHY IN EMMETROPIC, MYOPIC AND HYPEROPIC EYES

Purpose: The purpose of our study is to compare the average peripapillary retinal nerve fibre layer thickness by cirrus HD-Optical coherence tomography in emmetropic, axial myopic and axial hyperopic cases. Materials And Methods: Total of 120 subjects aged between 10 to 50 years were enrolled in this study, divided into 3 groups with 40 in each, namely group 1 - emmetropia, group 2- myopia >2.5 D and group 3-hypermetropia>2.5 D. In which, 58 (48.3%) were females and 62 (51.7%) were males. This study was done in the Department of Ophthalmology, Santhiram Medical College Hospital Nandyal,from October 2019 to March 2020. The average as well as quadratic assessment of peripapillary RNFL thickness by cirrus-HD optical coherence tomography and comparison among these 3 groups. Observation And Results: In our study, average peripapillary RNFL thickness between emmetropic, myopic and hyperopic groups was found to be statistically significant. The average peripapillary RNFL thickness was thickest in the hyperopic group (102.95 ± 5.629, n=40), followed by the emmetropic group (102.55 ± 5.505, n=40), and then the myopic group (83.38 ± 3.726, n=40) (all P<0.0001) . And in all four RNFL quadrants, myopic group showed thinning when compared to Emmetropic and hyperopic group (p<0.001).But hyperopic group showed thicker RNFL than emmetropic group only in temporal quadrants in right eye(p<0.001)and nasal and superior quadrants in left eye (p=0.017) Conclusion: In our study, average as well as in all the four quadrants peripapillary RNFL thickness shows highly significant results between emmetropia, myopia and hyperopia. When compared with emmetropia, RNFL thickness being thinnest in myopic group, and slightly thicker RNFL thickness in hyperopic group.