Experimental Animal Models of Fibrosis: Relevance and Considerations for Translational Health Research
Journal: International Journal of Zoology and Animal Biology (IZAB) (Vol.2, No. 3)Publication Date: 2019-04-24
Authors : Bindu S;
Page : 1-4
Keywords : Animal Models; Fibrosis;
Abstract
Tissue fibrosis is a set of progressive debilitating diseases which although initiate as a normal wound healing response to an injury, end up with hyperactivated immunological state leading to overwhelming deposition of extra cellular matrix (ECM) components by activated fibroblasts. About 45% deaths in the US are attributed to fibrosis-associated organ damage
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