State of Immunity and Methods of Correction in Patients with Ventral Abdominal Hernia on the Background of Chronic Uro-Genital Infection

The article considers resulting materials of examination and treatment of 88 patients (31 men, 57 women, the main group), aged 22-45 who applied to the Scientific Center of Surgery in order to have hernioplasty, in whom, chronic urogenital infections (CUGIs) were detected in various combinations viabacterioscopic, cultural and serological tests addressed to the research center of surgery for application of herniaplasty. Recurrent ventral hernia was diagnosed in 79 patients and umbilical hernia—in 9 patients. The control group consisted of 20 patients with hernias of the anterior abdominal wall, which did not have any chronic infections or concomitant diseases that negatively affect the parameters of immune system. The state of the cellular and humoral link of the immune system in patients with chronic urogenital infections was characterized by the presence of suppression in the T-cell link and an imbalance in the parameters of humoral immunity. The presence of clinical signs of immunodeficiency in patients with hernias of the anterior abdominal wall is a direct indication for the appointment of immune corrective therapy in the preoperative period. In patients with chronic urogenital infections, Likopid has a noticeable immune corrective effect, which is manifested in the form of positive dynamics of indicators of both cellular and humoral immunities; at the same time, Likopid therapy in combination with 0.33% saffron tincture is a more effective method of immune correction.