Assessment Quality of Life in Patient with Lip Cancer after Radical Surgery and Radiation Therapy

Lip cancer is one of the most frequent malignant neoplasms of the oral cavity. It has wide impact on the quality of life for patient and their families. In oncology, assessing quality of life is being used as a primary outcome measure to study the effectiveness of treatment therapy for cancer patient. Material and methods: This study included total of 103 patients affected by lip cancer (stage I-IV) who underwent treatment (surgery and radiation therapy) from 2010-2016 at Lviv Regional Oncological Centre, Department of Head and Neck Oncology, Lviv city. Quality of life (QOL) was assessed by using EORTC QLQ C30 V.30 Questionnaires and Head and Neck Cancer Specific Modules EORTC QLQ H&N35. All patients were divided into two groups, in which group-I consisted of 30 patients after radical surgery and in group-II consisted of 73 patients after radical radiation therapy. The QOL was assessed during one month after treatment of lip cancer. Result: In group-I (radical surgery therapy) 43% of patients had locally advanced disease with local metastasis to neck lymph nodes in 13% of cases. In this group G3 histological differentiation was strongly correlated with advance disease and poor prognosis. In group-II (radical radiation therapy) 88% of patients had mostly local disease (stages I-II). EORTC QLQ C30 and H&N35 score were better in group-II (radical radiation therapy) before treatment, than in group-I (radical radiation therapy). But one month after treatment group-I has better European Organization for Research and Treatment of Cancer (EORTC) score. Kaplan-Meier curve also shows better survival rate in group-I patients. Conclusion: Our results suggest that patient's quality of life is better when treated with radical surgery therapy and it also improves survival rate as compared with radical radiation therapy.