Polyomavirus among Transplanted Sudanese Patients

BK Polyomavirus is ubiquitous worldwide and latent in humans. Serologic evidence of previous exposure can be obtained in the majority of adults and immune-compromised subjects are more prone to viral reactivation [1], while kidney biopsies comparing a transplanted group of patients to normal subjects proved its exclusive existence among transplanted subjects [2]. It has been shown that one third of kidneytransplant subjects had asymptomatic viruria [3] and BK Polyomavirus associated nephropathy with graft was observed in 60 % of patients [4,5]. Diagnosing cases of BK Polyomavirus are effective in preventing progressive graft function and are widely recommended [6]. Therefore, there is a need for aggressive vigilance to detect the viral infection in its earlier stages before irreversible graft injury ensues. The current study was conducted to determine the incidence of BK Polyomavirus among transplanted Sudanese patients.