Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer
Journal: Journal of Applied Veterinary Sciences (Vol.6, No. 1)Publication Date: 2021-01-14
Authors : Safaa A. Warda; Naglaa I. Ali; Fatma F. Warda; Ekbal M. Farouk; Lubna F. Farahat;
Page : 21-27
Keywords : Carbomer; ELISA; SNT; Inactivated EHV-1; Equine Virus;
Abstract
An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares in comparison with the convention one adjuvanted with Al-hydra gel and saponin. Such purpose was established by using 0.5% carbomer as adjuvant to the inactivated EHV-1. The applied quality control tests carried out on such vaccine revealed that it is free from foreign contaminants, safe in pregnant mares and mice and potent induced high levels of specific EHV-1 antibodies in vaccinated Guinea pigs and mares as measure by ELISA and SNT. This immunity was sufficient to protect vaccinated horses up to 28 weeks (7months) post-vaccination.
Other Latest Articles
- Comparative Study For The Treatment Of Inactive Ovary In Local Iraqi Breed Cow By Using Massage Method Of The Ovaries And GnRH
- Evaluation Of Using Different Adjuvants Used For Preparation Of Staphylococcus Aureus Mastitis Vaccine On The Immune Response
- Verification Of Molecular And Conventional Techniques Used In The Diagnosis Of Equine Herpes Virus In Some Egyptian Governorates
- Traditional Medicines Prescription and the Potential of Original Indonesian Herbs as Natural Immunomodulators
- Review of Phytochemicals and Pharmacology of Medicinal Plants to Lower Blood Fat Levels
Last modified: 2021-03-13 06:32:47