Depletion of Antioxidants Vitamins and Oxidation of Low Density Lipoproteins observed among different workers with NIDDM Exposed to Vehicle Exhaust in the congested part of the CHENNAI city

This study was carried out among NIDDM patients who were exposed to traffic smoke more than 10hrs/day. We have measured the level of Vitamins, Vitamin C, Superoxide dismutase (SOD), Catalase, Oxidised LDL, Total thiols, Total cholesterol, plasma blood glucose, Urea, Creatinine and Urine sugar. It was found that the level of vitamin E, C, Catalase, total thiols was found to be depleted but the level of Oxidised LDL, LPO, LOH was found to be elevated. SOD was found to be slightly elevated, Common biochemical parameters plasma blood glucose, urea, creatinine was found to be increased. Most of the persons who participated in our study were NIDDM patients with varying degrees of severity of complications. The patients case histories were recorded which consist of the age, the hours of exposure to traffic smoke, the duration of diabetes in years. Sixty non-smoking males also participated as control. No Gross variation was observed in Lipid profile samples.