Synthesis, Characterization and Antibacterial activities of some Transition metal complexes with a new Mannich base (1-(3-furan-2-yl)-3-oxo-1-phenyl propyl)urea

A new Mannich base(1-(3-(furan-2-yl)-3-oxo-1-phenyl propyl)urea and its metal complexes with Co(II), Ni(II), Cu(II), Zn(II) ions have been synthesised and characterized. Their structural features have been established on the basis of analytical magnetic, conductance, IR, UV-Visible, Mass, 1H and 13C NMR spectra. The non electrolytic nature of the complexes was inferred from their low molar conductance values. On the basis of colour, magnetic moments and electronic spectal data, the geometries of Co(II), Ni(II), Cu(II), Zn(II) complexes were assigned. Cyclic voltammetric analysis of a Cu(II) complexes was discussed to understand the redox behaviour. The antibacterial activities of the ligand and a selected few complexes have been studied with the microorganisms such as Bacillus substillis, Staphylococcus aureus Escherichia Coli, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger, employing disc diffusion method. The ligand and the complexes possess significant antibacterial activity comparable to that of the standard drugs.