Synthesis of Mercapto Heterocyclic Derivatives of 1-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-thio-propan-1-one and its Biological Activities
Journal: Journal of Environmental Nanotechnology (Vol.6, No. 3)Publication Date: 2017-06-30
Authors : Venugopal; Dhandayutham; Manivachagam; Gnanaprakasam;
Page : 50-59
Keywords : ;
Abstract
In the present study, a new series of mercapto heterocyclic derivatives of 1-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)-2-thio-propan-1-one derivatives are synthesized. The chemical structures were confirmed by IR, 1H-NMR and mass spectral analysis. The compounds were screened for antibacterial and antifungal activity. It shows good antibacterial and antifungal activity for most of synthesized compounds.
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