Major Risk Factors for coronary atherosclerosis

BACKGROUND: The prevalence of early age atherosclerosis in India is increasing these days. The prevalence of atherosclerosis among individual which cause ischemic heart diseases is related to number of factors. There are several studies done on identifiable risk factors for coronary atherosclerosis. Objective: The objective of the study was to analyse the major risk factors (Age, Sex, Diabetes and Hypertension) for coronary atherosclerosis. MATERIALS AND METHODS: The study was carried out from January 2011 to June 2012 on 164 bodies received in department of Forensic Medicine, Government Medical College, Surat. The material of study comprised of all medico legal death. History of age, sex, diabetes, hypertension etc was taken. After gross examination, samples of hearts were examined for histo-pathological examination for grading of atherosclerosis. RESULTS: Out of total cases, 144 cases were of male and 20 cases were of female. Maximum (36) cases were in the age group of 40 to 50 years. A positive correlation of age, diabetes and hypertension was found with atherosclerosis. Multiple logistic regression analysis was done, independent demographic predictor of a good knowledge level was statistically significant (< 0.05), adjusted odd ratio was 4.01 for diabetes and 3.39 for hypertension. CONCLUSION: The study show definite correlation between risk factors and atherosclerosis. Certain lifestyle modification can decrease the incidence of atherosclerosis.