FDG embolism mimicking lung metastasis

2-[18F]-FDG embolism artifact is a PET pitfall that may cause misinterpretation as lung metastasis. This rare phenomenon results from clumping of the radiotracer with platelet aggregates during intravenous administration. It should be considered, especially if there is no corroborating anatomic correlate for focal pulmonary FDG activity and if the radiotracer is administered through a central venous catheter. Herein, we present images of a 3-year-old girl with history of abdominal neuroblastoma and lung metastasis, showing FDG embolism artifact, subsequently resolved in the repeat imaging. Our case reinforces the importance of knowing this artifact as misinterpretation can have a significant effect on patient management.