Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children
Journal: Medicni perspektivi (Vol.25, No. 4)Publication Date: 2020-12-28
Authors : Umanets T.R. Buratynska A.A. Tolkach S.I. Stepanova L.S. Matveeva S.Yu. Kondratenkova T.V. Smirnova O.A. Garaschenko T.A. Lapshyn V.F. Antipkin Yu.G.;
Page : 121-127
Keywords : children; asthma; gastroesophageal reflux disease; risk factors;
Abstract
The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (20 children with isolated asthma). Medical history data were collected through specially designed questionnaire for parents. It was determined that the perinatal risk factors that likely contributed to developing co-morbid asthma and GERD were a threatened miscarriage (OR=6.65; 95% CI, 1.7-25.6, p=0.003), acute respiratory illnesses during pregnancy (OR=6.52; 95% CI, 1.4-31.2, p=0.008), polyhydramnios (p=0.039) and uterine inertia (p=0.0003). Food hypersensitivity in the first year of life, the severity of asthma in examined children played role in increasing the risk of developing asthma combined with GERD (OR=4.83; 95% CI, 1.3-18.6, p=0.013 and OR=4.45; 95% CI, 1.2-17.1, р=0.019 respectively).
Other Latest Articles
- Endometrial state in women with uterine factor of infertility at the stage of preconceptional care according to sonography and doplerometry data
- Influence of motivated walking with partial body weight supporting on the gross motor functions in children with cerebral palsy
- Аdvanced glycation end-products as novel biomarkers of eosinophil-derived lung inflammatory diseases (literature review)
- Comparative analysis of aldehyde dehydrogenase 1 expression in polyps and adenocarcinoma of the distal colon
- The state of antioxidant defense system in young persons with gastroesophageal reflux disease and autoimmune thyroiditis
Last modified: 2021-05-27 02:22:03