PHARMACOLOGICAL IMPACT OF EDIBLE MACROFUNGI D. SPATHULARIA AND S. COMMUNE ON HEMATOLOGICAL PROFILE OF ALBINO RAT

Hematological investigations had been seen as helpful instruments in diagnosing the condition of wellbeing of an individual, the impact of food consumed can be assessed utilizing these apprehensions. In addition, the distinctive blood cell parameters are likewise helpful in the appraisal of immunological status of the individual. The present work was aimed to assess the impact of aqueous extract of edible macrofungiDacryopinaxspathularia and Schizophyllum commune on hematological parameters of albino rats. The two experimental macrofungi have been reported to possess several pharmacological properties like antioxidant, anti-diabetic, antibacterial, hepatoprotective, nephroprotective efficacies, and these are also used as traditional dietary and medicinal sources especially by the local people of North-east India. But the impact of these two edible macrofungi on the haematological parameters is still not reported. The results of the present work revealed that on administration of D. spathularia extract (500 mg/kg BW), slight but significant increase in total WBC count, platelets, eosinophils and monocytes was observed. There was no significant change found in rest of the hematological parameters. On the other hand, the administration of S. commune extract (500 mg/kg BW) had resulted into slight but significant increase in total WBC count and eosinophils, and rest all hematological parameters had not changed significantly. Thus, the two edible macrofungi under study does not have any adverse effects on haematological parameters and hence they are safe and can be used as dietary and nutraceutical purpose.