Iodine‐DMSO Catalyzed aromatization of Polysubstituted Cyclohexanone derivatives; An efficient methods for the synthesis of polyfunctionized Biaryls derivatives

Abstract We have developed a simple method for the regioselective aromatization of Polysubstituted Cyclohexanone derivatives in the presence of iodine (25 mol %), Pd/C (10Mol%) in dimethyl sulfoxide at 90 °C. , afforded functionalized biphenyls with at least one phenolic hydroxyl in moderate to very good yields. The present protocol contains a cheap catalyst, easy work up, normal reaction conditions, and high selectivity.