A REVIEW ON ADVANCED SEROTYPING METHODS FOR IDENTIFICATION OF KLEBSIELLA PNEUMONIAE CAPSULAR SEROTYPES

Identification of an organism plays an important role in diagnosis of diseases to understand the pathogenicity of that particular organism. Microorganisms differentiated by antigenic differences which are known as 'serotypes'. Liver abscess was recently recognized as a new invasive syndrome and serotyping serves as an important tool to distinguish strains of unusually virulent. During last ten years, highly reported incidents of liver abscess are of Klebsiella pneumonia. There are 78 capsular serotypes have been identified for Klebsiella pneumoniae which can be identified by using new advanced methods for serotyping of Klebsiella pneumoniae. Recent advanced capsular serotyping methods, more specifically molecular-based capsular serotyping methods. Even though, molecular serotyping has its limitation especially in sequencing, the limitations may be resolved with next generation sequencing (NGS). Advancement of serotyping is possible by development of convenient DNA mic