Stereotactic Body Radiation Therapy for Early - Stage, Inoperable Non-Small Cell Lung Cancer

Although surgery continues to be the standard of care for early-stage NSCLC, SBRT appears to provide comparable local control and survival to lobectomy.Several ongoing randomized trials (Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy Trial (VALOR), Stablemates, and Radical Resection versus Ablative Stereotactic Radiotherapy in Patients With Operable Stage I NSCLC (POSTILV) aim to answer this critical question of whether lobectomy or SBRT has superior tumor control and/or toxicity profile for early-stage operable NSCLC.Large amount of prospective data that lung SBRT is a highly effective and safe means by which to treat early-stage NSCLC.