Diabetic Retinopathy and its Relation with Serum Lipid and Serum Homocysteine Levels

Purpose: To study the relation of serum lipid levels and serum homocysteine levels with diabetic retinopathy. Method: Cross sectional study involving 82 type 2 diabetic patients with retinopathy evaluated between May 2017 to September 2018. 56 were males and 26 were females. Diabetic retinopathy was graded according to ETDRS classification. 50 patients had Non proliferative diabetic retinopathy and 32 patients had Proliferative diabetic retinopathy. Serum lipid and serum homocysteine was assessed for all. Glycemic control was assessed by FBS and HbA1c. Results: Analysis showed statistically significant correlation of serum cholesterol and serum triglyceride with NPDR,PDR and macular edema. Serum homocysteine was elevated in 28% of NPDR and 60% of PDR patients, with statistically significant relation seen with NPDR, PDR and CSME. Conclusion: Significant relation between serum cholesterol, triglyceride and homocysteine was seen in type 2 diabetics with retinopathy which implicates that these risk factors may contribute a role in progression of diabetic retinopathy.