Lot Depends on our SNPs for our Existence

SNPs present in coding, non-coding or in intergenic region of human DNA sequencecan impact in transcription, translation and deciding structure of the protein. When SNPs occur within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the gene's function or byaberrant proteins.Altered cellular metabolism caused by a specific SNPcan be useful for diagnosing its related disease.Hence,SNPs can act as biological markers, helping scientists locate genes that are associated with disease and so, it is important to prioritize and study those SNPs that falls in the regulatory region of the gene.