Management of Submandibular Abcess in Patients with Multiple Drug Resistance (MDR-TB)

One of the key treatment of odontogenic infection is adequate antibiotic regimen. The host factor play an important role in the prognosis of the patient. Patient with tuberculosis associated with malnutrition and anemia as the most common complications in TB sufferers. Multi-drug resistant (MDR-TB) defined as resistance to both isoniazid and rifampicin, the two most important first-line drugs in treating TB. Many research showed that Rifampicin were also quite effective in inhibiting the growth of orofacial bacteria. In this article, we present a case of one patient with odontogenic infection that has spread to submandible and submental spaces with history of previously failed TB treatment and currently diagnosed with MDR-TB. We performed surgical intervention by incision and drainage of pus, the provision of adequate broad spectrum antibiotic, and high calorie and high protein diet in order to ensure a better response to the treatment. Our patient showed a good and fast response to the combination of treatment that was given despite her systemic condition.