An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation

Novel 2-Methyl (2?-hydroxy-3?/5?-chloro-5?/3?-chloromethyl phenyl)- 3-( 3?/4?-sustitutedphenyl)-4-thiazolidones are synthesized from 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone in good yield with purity. The structure of these compounds are confirmed by IR, 1H NMR and Mass spectra of a representative member from the series .These novel derivatives are then screened for antibacterial and antifungal activities against S.aureus, E.coli, X.citri, E.carotovora, C.albicans, T.rubrum, A.solani and H.turcicum.