Predicting the Toxicity of Chemicals and Drugs using Machine Learning Models
Journal: International Journal of Science and Research (IJSR) (Vol.10, No. 4)Publication Date: 2021-04-05
Authors : Shraddha Surana;
Page : 1110-1114
Keywords : Machine Learning; Ensemble Learning; Toxicity Prediction;
- Pancreatic Tuberculosis-Report on a Rare Presentation of a Not So Rare Disease
- Rare Presentation of a Rare Orthopedic Pathology: Erdheim Chester Disease
- Isolated Tuberculosis of Gallbladder: Case Report of a Rare Disease with the Review of Literature
- Recurrent Bullous Diabeticorum Rare Presentation of a Common Disease: A Case Report
- A Rare Presentation of Human Parvovirus B19 in a Child with Sickle Cell Disease: Case Report and Review of the Literature
Abstract
Toxicity is the way to find out if the drug/medicine is harmful to human body. Currently, the toxicity of the medicine is calculated using in-vivo method, where the medicine is tested on the animals and their results are generated. However, this method of toxicity testing for all existing compounds biologically may not be viable financially and logistically. We try to solve this problem by using machine learning and deep learning techniques. We have used the ensemble learning algorithm voting based classifier [logistic regression, decision tree, support vector machines] to predict the toxicity of theTox21 dataset. Where we get the AUC (Area under Curve) of NR-AR-LBD: 0.87 SR-mmp: 0.84 NR-Ahr: 0.81 on these assays.
Other Latest Articles
- Study of Corrosion Resistance of Ferritic Stainless Steel 444 on Artificial Saliva
- Feelings and Motivation of COVID Ward Nurses: Psychological Impact of COVID 19
- A Study to Find out Effect of Mechanical Knee Traction versus IFT on Pain and Functional Disability in Patients with Knee Osteoarthritis - An Interventional Study
- To Evaluate the Effectiveness of Targeted Versus Syndromic Management in Women with Abnormal Vaginal Discharge
- Using Security Cameras, Doorbell Cameras, and Trap Cameras to Monitor the Behavior of Wild Boar (Sus Scrofa), in Liri, South East Pelion, Greece
Last modified: 2021-06-26 18:50:05