Pregnancy with Von Willebrand's Disease: A Case Report

Women experience naturally occurring physiological events such as menstruation, pregnancy and childbirth that put them at risk of excessive bleeding even if they do not have a bleeding disorder. In this paper the authors review a case of pregnancy in the third trimester with a history of von Willebrand's disease where the patient does not routinely control medication and includes the latest theoretical studies in order to provide benefits in clinical practice at a later date. The patient with the initials KAE, aged 25 years with history of von Willebrand's disease since the age of 17 but was not seen frequently. On laboratory examination, a mild microcytic hypochromic anemia was found with an increase in the value of activated partial thromboplastin time (APTT) increasing to 67.1 (normal value 24 to 36). In further examination, the von Willebrand factor result was less than 2%. After the patient reaches 39 weeks of gestation it is decided to terminate the pregnancy. Pregnancy termination is performed by induction of 25 mcg misoprostol every 6 hours if preparation is optimal with intravenous desmopressin therapy and administration of cryoprecipitate transfusion if bleeding occurs. After surgery, a baby girl was born crying with active movements. Physical examination found no congenital abnormalities in the baby and the birth weight was 3540 grams, body length was 48 cm and the APGAR score was 7 in the first minute and 8 in the fifth minute.