Observation of Prevalence of H. Pylori Infection in Patients with Sign and Symptoms of Dyspepsia at Patna Medical College and Hospital, Patna

Background: Helicobacter pylori are the most common chronic bacterial infection prevalent worldwide. It is a Gram negative, microaerophollic spiral shaped motile bacillus with ability to colonize normal human stomach mucosa. Aim: To study the prevalence of H. Pylori infection, in patients with sign and symptoms of dyspepsia, at PMCH, Patna with reference to age, sex and other risk factor that help in understanding the nature of disease. Methods: It is a clinical based cross sectional study that included patients ranging from 15 years to 75 years who were admitted at Patna Medical College with sign and symptoms of dyspepsia. From all enrolled patients history and routine as well as special investigations- Endoscopy and H pylori serological test were performed. Conclusion: Out of 91 patients, there were 53 male and 38 female patients, age ranging from 15 years to 75 years. 60 % of male patients were h.pylori positive, and 56% female were positive. H. Pylori was + in 74.19 % cases of Ulcer Dyspepsia, but only 40.38 % cases of Non Ulcer Dyspepsia. 84% cases of H.Pylori were positive for Duodenal ulcer, and 79% cases of H. Pylori for case of Gastric ulcer. 32 patients presented with sign and symptoms of dyspepsia, but the upper G.I endoscopy was normal, however out of 32 11 were found to be serological positive for Helicobacter pylori infection (34.37%).