Study the Effects of Signal Transduction Pathway in Teleosts Fish Melanophores

The fresh water Indian neopterigian teleost fish deals with some aspect concerning chromatic regulatory mechanisms, within the boundary of the two points of view: one of these is the value of colour pattern, as signals to other animals for the purpose of recognition, stimulation or warning or for the purpose of concealment of predator of prey. In this field is included the phenomenon of rapid colour change. The other point of view concerns the pharmacological nature of fiber which controls the activity of melanophores. Theophylline is a competitive nonselective phosphodiasterase inhibitor, which raises intracellular cAMP, activates PKA. Theophylline down regulates inflammatory and immune cell function in vitro in animals with airway inflammation. Theophylline increase the intracellular concentration of cyclic nucleotides in airway, smooth muscle and inflammatory cells by inhibiting phosphodiesterase-mediated hydrolysis.