Breaching the Gap between Clinical and Radiographic Diagnosis of Amelogenesis Imperfecta: A Review

Amelogenesis imperfecta encompasses a complicated group of conditions which demonstrate developmental alterations in the structure of enamel in the absence of systemic disorder or syndrome. A complex inheritance pattern gives rise to amelogenesis imperfecta. It affects the structure and appearance of enamel both in the primary and secondary dentition. Gene mutations which are responsible for deformed amelogenesis result in diverse phenotypes showing a wide spectrum of characteristics. It is important to understand the different phenotypes and associated radiographic findings related to AI to help narrow down the search for a candidate gene in order to establish a definitive molecular aetiology. Precise diagnosis of AI done by clinical and radiographic findings will help in stabilisation, restoration and regular maintenance of the patient.