Hand Schuller Christian Disease: A Case Report with Oral Manifestation

Langerhan?s cell histiocytosis is a group of diseases that result from langerhan?s cells or their precursors abnormal proliferation. The clinical manifestations are the result of infiltration and accumulation of the langerhan?s cells in tissues. We report a case of a three years? boy with osteolytic lesions involving occipital, maxillary and mandibular bone. Additional periodontal tissues destruction was seen involving all four quadrants. Diagnosis was confirmed radiographically and histologically.