Early Detection of Microvascular Complications in Asymptomatic Type 2 Diabetes Mellitus Patients and its Corelation with Glycosylated Haemoglobin

This study was conducted to find out diabetic nephropathy in asymptomatic patients of type 2 diabetes mellitus and its correlation with glycosylated haemoglobin. By identification of such patients, the chronic microvascular complications of diabetes mellitus can be curtailed at an early stage with best possible treatment outcome. The study was observational, descriptive conducted in the Department of General Medicine, D.Y Patil Hospital, Nerul, Navi Mumbai among 150 consecutive patients of Type 2 DM patients with duration of diabetes more than 6 months from the time of diagnosis over a period of Feb 2018- August 2019. Blood samples for fasting, postprandial blood sugar and renal function were collected; urine analysis for proteinuria; and HbA1c were carried out. All the subjects were evaluated for other confounding factors like hypertension. The mean age of the study population was 52.89 ± 5.84 with a range of 40 to 60 years. The study population comprised of 104 (69.3%) male patients and 46 (30.7%) female patients. The mean fasting, post prandial and HBA1C values among the study population was 195.64 ± 83.69, 259.10 ± 87.13 and 9.41 ± 2.85 respectively. The results of this study showed that the prevalence of diabetic nephropathy among study population were (28.7%). In our study diabetic nephropathy had statistically significant association with both HbA1c (p-0.013. The findings highlight the requirement for regular health evaluation and laboratory workup especially to look for asymptomatic hyperglycaemia to detect and treat DM in early stage and prevent complications.