Systemic Inflammatory Response Syndrome (SIRS) Outcome in Surgical Patients at Tertiary Care Hospital

Background: Occurrence of a postoperative systemic inflammatory response can increase risk of adverse outcomes. Systemic inflammatory response syndrome is a simple bed side tool to assess the severity of the patient’s disease process which gives the approximate idea about the outcome of the surgical patients. This study investigated the Systemic inflammatory response syndrome (SIRS) outcome in patients undergoing elective or emergency surgeries at tertiary care hospital Objectives: Systemic inflammatory response syndrome (SIRS) outcome in surgical patients at tertiary care hospital Methods: This was a prospective study conducted over a period of 2 years at GMC Amritsar. The total of 50 patients undergoing surgical procedures were studied. They were followed up till date of termination with daily SIRS monitoring, development of MODS and MOF. Statistical analysis was based on simple percentages among related variables. Results: Overall incidence of SIRS was 74%. Incidence of SIRS was more in patients undergoing emergency surgery than the patient who underwent elective surgery (43.47%). The difference was statistically significant. (pless than0.05). Increased age was associated with reduced inflammatory response in the postoperative period and might explain the greater benefit of anti-inflammatory prophylaxis in younger patients undergoing surgery. SIRS was more in males (78.57%). Duration of SIRS was more in patients undergoing Emergency surgery(4-5 days) than in elective group (3-4 days). Conclusion: The problems of inflammation and infection as a leading cause of organ dysfunction and failure is a major problem after surgery. SIRS is key pathogenic factor in postoperative morbidity which gives the approximate idea about the outcome of the surgical patients.