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A Short Synthesis of Carbazole Alkaloids Murrayanine and Mukonine
Journal: Chemical Methodologies (Vol.5, No. 4)Publication Date: 2021-07-01
Authors : Milind V. Gaikwad; Rahul D. Kamble; Shrikant V. Hese; Shuddhodan N. Kadam; Ajay N. Abhore; Sunil V. Gaikwad; Ashok P. Acharya; Bhaskar S. Dawane;
Page : 341-347
Keywords : Carbazole Alkaloids; Mukonine; Murrayanine; Buchard coupling;
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Abstract
The short, easy and total synthesis of Murrayanine (1), Mukonine (2), carbazole alkaloids were elaborated, based on a regioselective buchwald coupling of methyl 4-bromo-3-methoxybenzoate with aniline and successive transformation into the corrsponding carbazole alkaloids by oxidative coupling followed by cyclization of the phenyl and aryl rings.
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Last modified: 2021-06-27 22:47:33