Comprehensive Review on Synthesis and Evauation of Coumarins as Antimicrobials

Coumarins contain an outsized of phenolic compound obtained from plants and are manufactured from fused benzene and alpha pyrone ring. The prototypical compound is understood as 1, 2 benzopyrone Coumarin has mild antibacterial activity, but long chain hydrocarbon substituted compound like ammoresinol and ostruthin show wide spectrum activity against Gram +ve bacteria like Bacillus megaterium, Micrococcusluteus, Micrococcus lysodeikticus, and Staphylococcus aureus. Another coumarin compound anthogenol from green fruits of Aegle marmelos shows activity against Enterococcus. The target behind this review is to synthesise a brand new caumarin derivative which shows greater efficacy and potency with microbial growth.