Role of Dinoprostone PGE2 Gel Application on Feto-Maternal Outcome in Tertiary Care Centre

Background: Induction of labour is an intervention to artificially initiate uterine contractions leading to progressive dilatation and effacement of cervix and birth of baby. Recently, elective induction of labour at term have increased dramatically in the interest of mother or baby or both. Although Dinoprostone gel is considered as the preferred method for labour induction. Objective: Our study is being carried out to assess the efficacy of prostaglandin E2 gel and to watch the maternal and fetal outcome of labour after single versus double applications. Material and Methods: It was a Descriptive observational study carried in a Mathura das Mathur hospital Dr S N Medical College Jodhpur, a tertiary care hospital in Rajasthan. All women after 37th week’s gestation with single live fetus in cephalic presentation with a Bishop score less than6 and a reactive non-stress test were included in this study. Results: A total 300 patients studied and analysed to assess the efficacy of prostaglandin E2 gel and maternal and fetal outcome of labour after single versus double applications. Most common indication for induction with PGE2 gel was oligohydramnios (30.33 %) followed by HDOP (20.66 %). In single application group 61.33 %cases delivered vaginally while in cases of double application 74.66 % delivered vaginally. In our study LSCS delivery in single v/s double application was 34 v/s 23.33 % respectively. Maternal complications were in single application 18.67 % v/s double application 28 %.88 % of new born in single application had APGAR score of greater than7 and 92 % in double application had APGAR score of greater than7. In single application group new born delivered with APGAR score less than7 were 12 % cases and in double application were 8 %. Conclusion: Dinoprostone gel application is efficient in achieving cervical ripening and successful labour with reduction in latent phase of labour and total delivery time without increasing the rate of caesarean section and obstetric risk.