Histological Spectrum of Lesions in Nephrectomy Specimen - A Tertiary Care Hospital Experience

Background: Nephrectomy is the common surgical procedure done for variety of neoplastic and non-neoplastic disease. It is indicated in patients with wide range of clinical conditions ranging from symptomatic chronic infections, obstruction, calculus disease, end stage renal disease and severe traumatic injury to renal cell carcinomas. This study was conducted to find out the histopathological spectrum of diseases. Materials and Methods: This retrospective and prospective comparative study was carried on nephrectomy specimen received over the period of 3 years (February 2017 – January 2020) in department of pathology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand. Results: A total of 52 nephrectomy specimens were received. Male constituted 28 cases (53.8 %) and females 24 cases (46.2 %). Age ranges from 20 months to70 years. Non neoplastic (31 cases) were most common followed by malignant (21 cases). Chronic pyelonephritis (12 cases) was the most common. Among malignant tumour, renal cell carcinoma ( 11 cases) was most frequent. Conclusion: Non neoplastic lesions were more common than neoplastic lesion. Renal cell carcinoma was most common among the malignant tumours.