Correlation of Serum Leptin Serum Albumin and Haemoglobin with Outcome in Patients of Amoebic Liver Abscess

BACKGROUND: Amoebic liver abscess (ALA) is the third prime cause of parasitic infections related death. Management of ALA depends on size of abscess, segment/lobe of liver involved, complication of amoebic liver abscess, condition of patients and signs of peritonitis. Study aims to establish correlation of Serum Leptin, Serum Albumin and Haemoglobin with outcome in patients of Amoebic Liver Abscess. METHODS: This Prospective observational study carried out in Department of Surgery M. L. N. Medical College, Prayagraj. The diagnosis of Amoebic liver abscess was confirmed by serology. RESULTS: In our study out of total 64 patients, 90.62 % were males and 9.37 % were females. Male to female ratio was 10.6: 1. Mean age was 36.21 11.58. In our study 56 cases (87.5 %) abscesses were located in right lobe of liver and 4 (6.25 %) were located in left lobe of liver and remaining 4 (6.25 %) located in both lobe of liver. In our study patients with S. albumin greater than 3gm/dl, 75 % uncomplicated cases and 25 % complicated cases of ALA was noticed whereas patients with serum albumin (less than3gm/dl), 25 % uncomplicated cases and 75 % complicated cases of ALA noticed and longer duration of hospital stay was noticed with low serum albumin. Duration of hospital stay and complication of amoebic liver abscess patients with normal Serum Leptin was less in comparison to low Serum Leptin level patients. CONCLUSIONS: Amoebic liver abscess patients with low serum albumin, serum leptin and low haemoglobin levels had more complication rate and longer duration of hospital stay.