Spectrum of Pathogenic Bacteria Isolated from the Endotracheal Tube Aspirates and their Antibiotic Sensitivity Pattern in a Tertiary Care Centre Ranchi

Background: Pneumonia is the inflammation of the lung tissue caused by infection of bacteria, virus, fungi. Several bacterial etiological agents are known to cause the infection, studies have shown several gram negative bacteria including Pseudomonas spp, Klebsiella spp and gram positive bacteria such as Streptococcus spp are known to cause infection. In the present study we aim to evaluate the spectrum of bacterial isolates and their antibiotic sensitivity pattern isolated from Endotracheal tube aspirates. (ETA) Materials and Methods: The retrospective study was carried out in a tertiary care centre over a period of fifteen months of total 858 ETA samples. The isolates were evaluated and identified with antibiotic sensitivity pattern. Results: The overall ETA specimen processed in 15 months were 858, in which culture were positive in 582 cases (69 %). The organisms isolated were Klebsiella pneumoniae grown in 309 samples (53 %), Pseudomonas aeruginosa, grown in 157 samples (27 %), Escherichia. coli grown in 64 samples (11 %), Proteus grown in 11 (2 %) and Methicillin resistant Staphylococcus aureus grown in 40 samples (7 %). Most of Klebsiella pneumoniae isolates came sensitive to Colistin and Pseudomonas aeruginosa came sensitive to colistin, Meropenem, Imipenem. Conclusion: The present study has shown the most common isolate at our tertiary centre wasKlebsiella spp, followed byPseudomonas aeruginosa, Escherichia. coli and Proteus in gram positive bacteria the common organism isolated was Staphylococcus aureus. Our results contribute to evaluate the common prevalent organisms causing pneumonia and also helps in improving the epidemiological knowledge