Pharmacological Activities of 6-substituted-3-(5-chloro-3-phenyl-1H-indole-2yl)-3, 4-dihydro-4-substituted-4-substituted-phenacyl-2H-1, 3-benzoxazin-2-ones
Journal: International Journal of Science and Research (IJSR) (Vol.9, No. 7)Publication Date: 2020-07-05
Authors : S. M. Basavarajaiah; B. H. M. Mruthyunjayaswamy;
Page : 518-521
Keywords : Indoles; Chalcones; Benzoxazin-2-ones; Pharmacological activities;
Abstract
In the present investigation, a series of new 4-substituted-2- [ (E) - (4substituted-phenyl) -oxoprop-1-enyl]-phenyl-5’chloro-3’-phenyl-1’H-indol-2’yl-carbamates (6a-f) and 6-substituted-3- (5’-chloro-3’-phenyl-1’H-indole-2’yl) -3, 4-dihydro-4-substituted-phenacyl-2H-1, 3-benzoxazin-2-ones (7a-f) were screened for their pharmacological activities like anti-inflammatory and analgesic activities.
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