Effect of extrac purple Ipomoe Batatas cultivar kawi mountain chronic inflammation in Wistar Rats with atherogenic diet

The potential biological functions of purple Ipomoea Batatas cultivar kawi mountain (IBCK). anthocyanin from purple Ipomoea Batatas cultivar Kawi mountain have long been described in traditional system of medicine. However, the protective effect of atherogenensis is still unknown. The present study attempted to investigate the protective effect of extract purple Ipomoea Batatas cultivar kawi mountain against foam cell and chronic inflammation in Wistar rats with atherogenic diet. The biochemical atherogenesis CD40L, NFκβ and histopathological foam cells changes were examined. Our results show that the pretreatment with extract purple Ipomoea Batatas kultivar kawi mountain (20mg/kgBW) orally revealed attenuation of cytokines activities of CD40L, NFκβ and decreased formation of foam cells in wistar rats with atherogenic diet.