A Cross Sectional Comparative Non Randomized Interventional Cohort Study to Assess the Weight and Sepsis Rate among Pre Term Babies Receiving TPN and Not Receiving TPN at Selected Hospitals of Indore in the Year 2015-2016

Parentral nutrition is an essential component in the management of many newborn infants, particularly in premature low birth weight infants admitted to newborn intensive care units4 The present study was a cross sectional comparative non randomized interventional cohort study design adopted to assess the net cumulative weight loss and weight gain as well as sepsis rate among pre term babies admitted in neonatal intensive care unit of Choithram Hospital and Research Centre, Indore. The study was conducted among 30 pre term babies selected through multi stage sampling technique, i. e pre term babies were selected using purposive sampling technique and then convenient sampling technique was used to put pre term babies 15 in experimental and 15 in control group. The pre term babies receiving Total parentral nutrition had more weight gain compared to preterm babies not receiving Total parentral nutrition assessed on Day1, 3, 5& 7 as well as the percentage of weight loss was decreased in preterm babies receiving total parentral nutrition. There was significant change in the biochemical parameters CBC (Hb, MCV, Platelets) sodium, potassium, chloride, calcium, CRP and blood culture in both the groups. There were 7 (47 %) of babies who had sepsis in control group who were not receiving total parentral nutrition compared to 3 (20 %) of preterm babies had sepsis in experimental group who were receiving total parentral nutrition