Prevalence of IS256 in Multidrug Resistance Stphylococcus aureus Isolated from Clinical Samples

staphylococcus aureus is a maior human pathogen and has been able to acquire resistance to nearly all clinically used antibiotics. This study was conducted to investigate the genetic organization of IS256 in clinical isolates of S. aureus. A total of 22 isolates of S. aureus from nosocomial infections were collected, identified, and examined to determine the distribution of IS256 residing in genomic DNA of these isolates. Results showed that 18 (83 %) of these isolates are multidrug resistance, the MOreover, detection of IS256 was found to be associated with antibiotic resistance in these clinical isolates. The data suggest that IS256 is a characteristic element in the genome of multiresistance nosocomial S. aureus isolates.